Endocrine Abstracts

The renin–angiotensin system is known to enhance erythropoiesis. (Pro)renin receptor ((P)RR), a specific receptor for renin and prorenin, has recently been identified. We have recently shown expression of (P)RR in a human erythroid cell line, YN-1. It is known that triiodothyronine (T3) and angiotensin-II (A-II) stimulate proliferation of erythroid cells. The aim of the present study is to clarify effects of T3 and A-II on expression of (P)RR in the ...

Primary aldosteronism (PA) is the most major cause of secondary hypertension, with its prevalence ranging from 3 to 20% of the hypertensive patients. Although guideline for diagnosis of PA has been established by the Endocrine Society, details of its applicability remain to be elucidated. In this study, we investigated the applicability of each step of the guideline in hypertensive patients by the multi-center collaborative study of National Hospital Organization (NHO) in Japa...